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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2020, Vol 7, Issue 1
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Original Article
Reproductive And Menstrualrisk Factors For Endometriosis Disease: A Case-Control Study
Sanaz Mollazadeh1, Mahin Kamalifard2, Behnaz Sadeghzadeh Oskouei2, Nayyereh Aminisani3, Mehri Jafari Shobeiri4, Mojgan Mirghafourvand5
1Students' Research committee, Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
2Department of Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
3Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran
4Faculty of Medicine , Tabriz University of Medical Sciences, Tabriz, Iran
5Social Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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Keywords : Case-control study, Endometriosis;Menstrual characteristics, Reproductive characteristics
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Objectives: The endometriosis prevalence in the generalpopulationis about 7-10¬%. In 30% of women, endometriosis is one of the causes for primary and secondaryinfertility. There are various risk factors for this disease. The present study aimed to determinereproductive and menstrual risk factors of endometriosis.

Materials and Methods: In this case-control study, 185 women of reproductive age with confirmed endometriosis were compared with 370 women of reproductive age that referred to the same center for other problems in terms of reproductive and menstruation risk factors for endometriosis The two groups were matched for age. Data were collected using a researcher-made questionnaire based on previous studies. Bivariate analysis was done by the chi-square test and multivariate analysis was done by the conditional logistic regression for controlling the confounder variables.

Results: Based on multivariate logistic regression,early menarche age (p=0.004), no history of pregnancy (p<0.001), no child (p=0.002), no lactation history (p<0.001), high age of first lactation (p=0.029), short duration of breastfeeding (p=0.015), no regular menstruation (p<0.001), short interval between menstrual bleeding (p=0.016), prolonged Menstruation (p<0.001), dysmenorrhea (p<0.001), dyspareunia (p<0.001), and recurrent vaginitis (p<0.001) had a significant relationship with endometriosis.

Conclusions: There is a relationshipbetween some reproductive and menstrual characteristics with endometriosis.Therefore, it seems that menstrual and reproductive characteristics can predict the occurrence of endometriosis disease.


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