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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2020, Vol 7, Issue 1
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Original Article
Determining the Efficacy of Some Hospital Disinfectants on Methicillin-Resistant Staphylococci Isolated from Different Wards of an Educational Hospital
Seyed Ali Sajjadi1, Jalal Mardaneh2, Alireza Mohammadzadeh2, Roghye Hojjatpanah3, HosseinNezami4, Mostafa Amiri5, Mehdi Ghasemi1
1Department of Environment Health Engineering & Social Determinants of Health Research Centre, Faculty of Health, Gonabad University of Medical Sciences, Gonabad, Iran
2Department of Microbiology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran
3Student Research Committee, Department of Environment Health Engineering, Faculty of Health, Gonabad University of Medical Sciences, Gonabad, Iran
4Department of Basic Sciences, Faculty of Medicine, Social development and health promotion research center,Gonabad University of Medical Sciences, Gonabad, Iran
5Department of Basic Sciences, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran

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Keywords : MRAS, Staphylococcusepidermidis,Staphylococcussaprophyticus,disinfectants, nosocomial infections
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Objectives: Methicillin-resistant staphylococci are important causes of nosocomial infections. According to the presence of these bacteria in hospitals as a significant challenge in hospital infection control, the identification of effective disinfectants for methicillin-resistant staphylococci is necessary. This study was designed to evaluate the effectiveness of common hospital disinfectants on methicillin-resistant staphylococci.

Materials and Methods: In the presentstudy (cross-sectional study), evaluation of the effectiveness of four surface disinfectant cleaners (Deconecx 50 AF, Microzed GP-H, Peranacid M1 and Surfocept quick) against methicillin-resistant staphylococci (10 Staphylococcus aureus,10 Staphylococcussaprophyticus and 55 Staphylococcusepidermidis) was performed usingbroth dilution method, disc diffusion assay, and cell viability assay.

Results:“The minimum inhibitoryconcentrations(MICs)” and“minimum bactericidal concentrations (MBCs)”of peranacid and surfoceptfor the isolates were higher than those of deconecx and microzed. The results of disk diffusion assay showed that staphylococcus strains had higher inhibition zone diameter than other disinfectants at different concentrations of deconex and microzed. According to the results of cell viability assay, S.aureus, S.epidermidis, and S.saprophyticus isolates did not grow at three concentrations of 0.5%, 1% and 2%, fordeconex, microzed and peranacid, respectively.

Conclusions:Thedeconex and microzed had more antimicrobial properties than the two other agents and methicillin-resistant staphylococcus isolates had a higher resistance to both peranacid and surfosept.


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Articles by Ali Sajjadi S
Articles by Mardaneh J
Articles by Mohammadzadeh A
Articles by Hojjatpanah R
Articles by Hosseinnezami H
Articles by Amiri M
Articles by Ghasemi M


Articles by Seyed Ali Sajjadi
Articles by Jalal Mardaneh
Articles by Roghye Hojjatpanah
Articles by HosseinNezami
Articles by Mostafa Amiri
Articles by Mehdi Ghasemi

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