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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Oct 2019, Vol 6, Issue 4
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Topical Oral Medicaments in Traditional Persian Medicine
Zoleikha Khoshbakht1, Mohammad Ali Torbati2, Laleh Khodaie3, Ehsan Khashabi4
1Department of Phytopharmacy, Faculty of Traditional Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
4Department of periodontics, Faculty of Dentistry, Urmia University of Medical Sciences, Urmia, Iran

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Keywords : Ethno-medicine, Ethno-pharmacology, Traditional persian medicine, Topical oral drugs
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Objectives: Traditional, topically used oral medicament are of great importance in the treatment of both oral and systemic diseases.The aim of this study is to review the indications of various drug delivery forms and active ingredients of currently used medications in complementary medicine, as well as the results of recent research to find any possible conformity between their traditional and recent pharmaceutical properties.

Materials and MethodsIn this review article comprehensive search of resources including electronica databases, hand searching, screening of reference lists and contacting experts were performed and the extracted data were categorized.

Results: The results indicated that there were six drug forms in gaseous, liquid and solid states with more than 70 formulations. Liquid and gaseous forms were mainly used for management of systemic conditions and solid forms were mainly applied for local treatments. Investigating about 50 herbal components showed that the traditional therapeutic effects of the vast majority of the ingredients were parallel with recent studies. While there are no clinical studies regarding the traditionally mentioned systemic effects after topical use of this medicament in the form of gargles or mouth rinse.

Conclusion: The side effects of oral and inject able drugs on one hand, and the specific advantages of oral mucosain achieving the topical and systemic effects besides the variety of the plant components of Iranian traditional oral medicament, might have  high potentials for finding new drugs and  improving treatment strategy  of some  systemic diseases such asCNS diseases and Depression.


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