Login Contact Us
E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Oct 2020, Vol 7, Issue 4
Advanced Search
How do you find the scientific quality of the published articles on our web site?
Therapeutic Effects of Citrus aurantium Components on Psychological States: A Systematic Review
Farkhondeh Aboualsoltani1, Parvin Bastani2, Laleh Khodaie3, Seyyed Mohammad Bagher Fazljou1
1Department of Persian Medicine, School of Traditional Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3Department of Traditional Pharmacy, School of Traditional Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

CJMB 2020; 7: 443-450

Viewed : 3193 times
Downloaded : 2500 times.

Keywords : Citrus aurantium, Bitter orange, Treatment, Therapeutic effects
Full Text(PDF) | Related Articles
Objectives: Citrus aurantium L., frequently known as the sour or bitter orange, is native to Asia and, nowadays, is widely cultivated in different regions such as the Mediterranean. Different parts of C. aurantium are consumed as an alternative medicine in some areas to treat some diseases, and various recent studies have proven the potential of this medicinal plant. This review examined the therapeutic effects of C. aurantium components.

Methods: Tactful and progressive search strategies were developed to determine the studies. To this end, a large number of databases were evaluated, including Cochrane Library, PubMed/MEDLINE, Scopus, and Google Scholar (2010 to April 2019). Finally, 12 clinical trial studies were selected for evaluation and analysis, and the JADAD scale was used to evaluate the quality of the papers.

Results: Of 546 papers found in the preliminary search, 12 clinical trials (1132 participants), which were written in English, were selected for structured reviews. The researches consisted of those which evaluated the therapeutic role of the plants in anxiety, depression, sleep quality, premenstrual syndrome, and menopausal symptoms.

Conclusions: The review of clinical trials brings some evidence that different components of C. aurantium, especially its flower have therapeutic effects on particularly psychological states like anxiety, depression, and insomnia and aromatherapy by the essential oil is considered as the most used method of prescription. Therefore, C. aurantium can confidently be used in various disorders which have these psychological aspects among their symptoms.


Cite By, Google Scholar

Google Scholar

Articles by Aboualsoltani F
Articles by Bastani P
Articles by Khodaie L


Articles by Parvin Bastani
Articles by Laleh Khodaie

Submit Paper
Online Submission System
CJMB ENDNOTE ® Style Tutorials Publication Charge Women's Reproductive Health Research Center About Journal
Publication Information
Aras Part Medical International Press Editor-in-Chief
Arash Khaki
Deputy Editor
Zafer Akan
Published Article Statistics